If it's an option, heat. But we're talking about 250°C so it may not be a good idea for everything; at high temps Loctite reverts to liquid form. The actual temperature varies from color to color/between products, the bottle or package should indicate its temperature limits.
Obviously the parts and screws will be really hot, so handle with care.
Otherwise, for medium... should come loose with enough torque (you may need to use something like a ratchet wrench with a screw driver bit adapter). Go slowly and work the screw back and forth gradually to break up the thread lock. But depending on how strong it is, and the quality of the materials, there's a risk you'll mess up your threads.